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Recombinant human ERK1/ERK2 protein
Recombinant human ERK1/ERK2 protein
规格:
货期:
编号:TSENZ2249
品牌:Testobio
基因名 ERK1/ERK2
英文全称 Mitogen-activated protein kinase 1
别称 ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2
中文名称 丝裂原活化蛋白激酶1;丝裂原活化蛋白激酶2
Uniprot P28482
GeneID 5594
交叉反应(推测) Human Mouse Rat (Bovine Monkey Gorilla)
氨基酸大小 41kDa
表达氨基酸 1-360aa
Background The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER).This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro.This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair.This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Application Immunology research
Derived from E.coli
Purification NI-NTA affinity purification
Formulation Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0.
Shipping The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity Purity≥85% as determined by reducing SDS-PAGE.
规格 10ug 50ug 100ug 1mg
合作单位: