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基因名 | PLAAT3 |
英文全称 | Phospholipase A and acyltransferase 3 |
别称 | PLA2G16; AdPLA; H-REV107; H-REV107-1; HRASLS3; HREV107; HREV107-1; HREV107-3; HRSL3; HRAS-like suppressor 3 |
中文名称 | 磷脂酶A及脂肪酰转移酶3 |
Uniprot | P53816 |
GeneID | 11145 |
交叉反应(推测) | Human Mouse Rat (Gorilla) |
氨基酸大小 | 18kDa |
表达氨基酸 | 1-162aa |
Background | Lipid-modifying enzyme that acts as major regulator of adipocyte lipolysis by catalyzing the release of fatty acids from phospholipids in adipose tissue .Shows phospholipase A1 and A2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE) .For most substrates, phospholipase A1 activity is much higher than phospholipase A2 activity .Phospholipase activity causes decreased intracellular levels of ether-type lipids, affecting peroxisome metabolism (By similarity).May also have acyltransferase activity: catalyzes both N-acylation of phosphatidylethanolamine to form N-acyl-phosphatidylethanolamine and O-acylation of lyso-phosphatidylcholines to form phosphatidylcholines.The relevance of acyltransferase activity in vivo is however unclear and would require additional evidences.Also has weak lysophospholipase activity (By similarity). |
Application | Immunology research |
Derived from | E.coli |
Purification | NI-NTA affinity purification |
Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity | Purity≥85% as determined by reducing SDS-PAGE. |
规格 | 10ug 50ug 100ug 1mg |