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基因名 | PTPN7 |
英文全称 | protein tyrosine phosphatase, non-receptor type 7 |
别称 | BPTP 4, HEPTP, LC PTP, LPTP, PTPN7, PTPNI |
中文名称 | 非受体7型蛋白酪氨酸磷酸酶 |
Uniprot | P35236 |
GeneID | 5778 |
交叉反应(推测) | Human Mouse Rat |
氨基酸大小 | 41kDa |
表达氨基酸 | 1-350aa |
Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells.The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities.This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway.Multiple alternatively spliced transcript variants have been found for this gene. |
Application | Immunology research |
Derived from | E.coli |
Purification | NI-NTA affinity purification |
Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity | Purity≥85% as determined by reducing SDS-PAGE. |
规格 | 10ug 50ug 100ug 1mg |