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Recombinant human DSE protein
Recombinant human DSE protein
规格:
货期:
编号:TSENZ2410
品牌:Testobio
基因名 DSE
英文全称 dermatan sulfate epimerase
别称 dermatan sulfate epimerase, DS epimerase, DSE, DSEPI, SART 2, SART2
中文名称 硫酸皮肤素差向异构酶
Uniprot Q9UL01
GeneID 29940
交叉反应(推测) Human Mouse (Bovine)
氨基酸大小 40kDa
表达氨基酸 609-958aa
Background The protein encoded by this gene is a tumor-rejection antigen.It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate.This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy.Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome.Alternative splicing results in multiple transcript variants.A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18.
Application Immunology research
Derived from E.coli
Purification NI-NTA affinity purification
Formulation Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0.
Shipping The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity Purity≥85% as determined by reducing SDS-PAGE.
规格 10ug 50ug 100ug 1mg
合作单位: