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Recombinant human GPI protein
Recombinant human GPI protein
规格:
货期:
编号:TSENZ2413
品牌:Testobio
基因名 GPI
英文全称 glucose phosphate isomerase
别称 AMF; GNPI; NLK; PGI; PHI; SA-36; SA36; glucose-6-phosphate isomerase
中文名称 葡萄糖磷酸异构酶
Uniprot P06744
GeneID 2821
交叉反应(推测) Human Mouse (Zebrafish)
氨基酸大小 40kDa
表达氨基酸 1-350aa
Background This gene encodes a member of the glucose phosphate isomerase protein family.The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate.Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion.The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor.Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.Alternative splicing results in multiple transcript variants.
Application Immunology research
Derived from E.coli
Purification NI-NTA affinity purification
Formulation Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0.
Shipping The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity Purity≥85% as determined by reducing SDS-PAGE.
规格 10ug 50ug 100ug 1mg
合作单位: